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In enzymology, a (+)-delta-cadinene synthase () is an enzyme that catalyzes the chemical reaction :2-trans,6-trans-farnesyl diphosphate (+)-delta-cadinene + diphosphate Hence, this enzyme has one substrate, 2-trans,6-trans-farnesyl diphosphate, and two products, (+)-delta-cadinene and diphosphate. This enzyme belongs to the family of lyases, specifically those carbon-oxygen lyases acting on phosphates. The systematic name of this enzyme class is 2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase (cyclizing, (+)-delta-cadinene-forming). This enzyme participates in terpenoid biosynthesis. It employs one cofactor, magnesium. Delta-cadinene synthase, a sesquiterpene cyclase, is an enzyme expressed in plants that catalyzes a cyclization reaction in terpenoid biosynthesis. The enzyme cyclizes farnesyl diphosphate to delta-cadinene and releases pyrophosphate. Delta-cadinene synthase is one of the key steps in the synthesis of gossypol, a toxic terpenoid produced in cotton seeds. Recently, cotton plants that stably underexpress the enzyme in seeds have been developed using RNA interference techniques, producing a plant that had been proposed as a rich source of dietary protein for developing countries.〔Sunilkumar G, Campbell L, Puckhaber L, Stipanovic R, Rathore K (2006). "Engineering cottonseed for use in human nutrition by tissue-specific reduction of toxic gossypol". ''Proc Natl Acad Sci U S A'' 103 (48): 18054-9. PMID 17110445〕 ==External links== * (BRENDA entry ) * (SwissProt entry ) 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Delta-cadinene synthase」の詳細全文を読む スポンサード リンク
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